BIM-23056 (TFA)

BIM 23056 TFA, a linear octapeptide, is a potent sst3 and sst5 somatostatin receptor antagonist with Ki values of 10.8, 5.7, respectively[1].

Product Specifications

CAS Number

[1426173-61-6]

UNSPSC

12352209

Target

Somatostatin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bim-23056-tfa.html

Solubility

H2O

Smiles

OC(C(F)(F)F)=O.OC(C=C1)=CC=C1C[C@H](NC([C@@H](NC([C@H](N)CC2=CC=CC=C2)=O)CC3=CC=CC=C3)=O)C(N[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@@H](C(N)=O)CC4=CC5=C(C=CC=C5)C=C4)=O)CC6=CC=CC=C6)=O)=O)=O)CC7=CNC8=CC=CC=C78)=O

Molecular Formula

C73H82F3N11O11

Molecular Weight

1346.49

References & Citations

[1]Y C Patel, et al. Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5) . Endocrinology. 1994 Dec;135 (6) :2814-7.|[2]W Feniuk, et al. Further evidence from functional studies for somatostatin receptor heterogeneity in guinea-pig isolated ileum, vas deferens and right atrium. Br J Pharmacol. 1995 Jul;115 (6) :975-80.