OCLN Polyclonal Antibody
Product Specifications
Background
Occludin is an integral membrane protein located at the tight junction. It is a tetraspanin protein with four transmembrane domains, intracellular N and C termini and two extracellular loops. Occludin plays a role in the formation and regulation of the tight junction paracellular permeability barrier. Occludin can exist in different isoforms, owing to modifications at the posttranscriptional and posttranslational levels .
Abbreviation
OCLN
UniProt
Q61146, Q6P6T5
Host
Rabbit
Reactivity
Mouse
Immunogen
Recombinant protein corresponding to Mouse occludin
Target
BLCPMG; FLJ08163; FLJ18079; FLJ77961; FLJ94056; MGC34277; Occludin; Ocln; OCLN; Phosphatase 1 regulatory subunit 115; PPP1R115; PTORCH1; Tight junction protein occludin
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Signal Transduction
Purification
Affinity purification
Concentration
0.56 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
59kDa
Observed Molecular Weight
60kDa
Citation 01
https://link.springer.com/article/10.1007/s00213-020-05605-w
Citation 02
https://www.sciencedirect.com/science/article/pii/S1382668920300880
Isotype
IgG
Available Sizes
Documents
Curated Selection
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