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OCLN Polyclonal Antibody

Product Specifications

Background

Occludin is an integral membrane protein located at the tight junction. It is a tetraspanin protein with four transmembrane domains, intracellular N and C termini and two extracellular loops. Occludin plays a role in the formation and regulation of the tight junction paracellular permeability barrier. Occludin can exist in different isoforms, owing to modifications at the posttranscriptional and posttranslational levels .

Abbreviation

OCLN

UniProt

Q61146, Q6P6T5

Host

Rabbit

Reactivity

Mouse

Immunogen

Recombinant protein corresponding to Mouse occludin

Target

BLCPMG; FLJ08163; FLJ18079; FLJ77961; FLJ94056; MGC34277; Occludin; Ocln; OCLN; Phosphatase 1 regulatory subunit 115; PPP1R115; PTORCH1; Tight junction protein occludin

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Signal Transduction

Purification

Affinity purification

Concentration

0.56 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

59kDa

Observed Molecular Weight

60kDa

Citation 01

https://link.springer.com/article/10.1007/s00213-020-05605-w

Citation 02

https://www.sciencedirect.com/science/article/pii/S1382668920300880

Isotype

IgG

Available Sizes

Curated Selection

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