CCNT2 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein.
Abbreviation
CCNT2
UniProt
O60583
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human CCNT2
Target
CCNT2; CCNT2; Cyclin T2a; Cyclin T2b; Cyclin-T2; CycT2; FLJ90560; MGC134840; SDS stable vimentin bound DNA fragment HEF42VIM22; Subunit of positive elongation transcription factor b
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling
Purification
Antigen affinity purification
Concentration
0.8 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
81 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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