PCNA Polyclonal Antibody
Product Specifications
Background
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Abbreviation
PCNA
UniProt
P12004
Host
Rabbit
Reactivity
Human; Mouse; Rat; Monkey
Immunogen
Synthesized peptide derived from the Internal region of human PCNA
Target
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; PCNA; Pcna/cyclin; PCNA; PCNAR; Polymerase delta accessory protein; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Tags and Cell Markers
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29kDa
Observed Molecular Weight
36kDa
Isotype
IgG
Available Sizes
Curated Selection
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