JAM3 Polyclonal Antibody
Product Specifications
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.
Abbreviation
JAM3
UniProt
Q9BX67
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human JAM3
Target
FLJ14529; JAM 2 ; JAM 3; JAM C; JAM-2; JAM-3; JAM-C; JAM2 ; Jam3; JAM3; JAMC; Junctional adhesion molecule 3; Junctional adhesion molecule 3 precursor; Junctional adhesion molecule C
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cardiovascular; Signal Transduction; Tags; Cell Markers
Purification
Antigen affinity purification
Concentration
1.08 mg/mL
Dilution
IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/hlwwep
Product MSDS
https://789.bio/eb/XLOa1O
Isotype
IgG
Available Sizes
Curated Selection
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