BCL2 Polyclonal Antibody

Product Specifications

Background

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

Abbreviation

BCL2

UniProt

P10415

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide of human BCL2

Target

Apoptosis regulator Bcl 2; Apoptosis regulator Bcl-2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; Bcl-2; Bcl2; BCL2; C430015F12Rik; D630044D05Rik; D830018M01Rik; Leukemia/lymphoma; B-cell;2; Oncogene B-cell leukemia 2; PPP1R50; Protein phosphatase 1; regulatory subunit 50

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Field of Research

Cancer; Cell Biology; Metabolism; Signal Transduction

Purification

Affinity purification

Concentration

0.6 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

22kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S1043661822003930

Citation 02

https://www.mdpi.com/1975256

Citation 03

https://www.mdpi.com/1574002

Citation 04

https://www.mdpi.com/1422-0067/22/15/8117

Citation 05

https://www.spandidos-publications.com/10.3892/ijmm.2019.4432

Citation 06

https://onlinelibrary.wiley.com/doi/abs/10.1002/mrd.23280

Citation 07

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773939/

Isotype

IgG

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