RAP1A Polyclonal Antibody
Product Specifications
Background
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
Abbreviation
RAP1A
UniProt
P62834
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human RAP1A
Target
C21KG; G-22K; GTP-binding protein smg p21A; KREV1; RAP1A; RAP1A; member of RAS oncogene family; RAP1A; Ras-related protein 1A; Ras-related protein Krev-1; Ras-related protein Rap-1A; SMGP21
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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