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BCAT1 Polyclonal Antibody

Product Specifications

Background

This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.

Abbreviation

BCAT1

UniProt

P54687

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant protein of human BCAT1

Target

BCAT; BCAT (c) ; Bcat1; BCAT1; BCT1; Branched chain amino acid aminotransferase; cytosolic; branched chain amino-acid transaminase 1; cytosolic; branched chain aminotransferase 1; branched chain aminotransferase 1; cytosolic; Branched-chain-amino-acid aminotransferase; cytosolic; DKFZp686E12175; EC 2.6.1.42; ECA39; MECA39; placental protein 18; PNAS 121; PP18; Protein ECA39

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Metabolism; Signal Transduction

Purification

Affinity purification

Concentration

0.4 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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