VPC01091.4
VPC01091.4 (VPC4) is a TRPM7 inhibitor and blocks TRPM7 current at low micromolar concentrations. VPC01091.4 can penetrate the blood-brain barrier. VPC01091.4 is an efficacious anti-inflammatory agent that arrests systemic inflammation in vivo[1].
Product Specifications
CAS Number
[945604-76-2]
Product Name Alternative
VPC4
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vpc01091-4.html
Purity
98.04
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCCCCCC1=CC=C([C@@H]2CC[C@@](CO)(C2)N)C=C1
Molecular Formula
C20H33NO
Molecular Weight
303.48
References & Citations
[1]Gregory W, et al. Novel TRPM7 inhibitors with potent anti-inflammatory effects in vivo.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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