Benzophenone

Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity[1][2].

Product Specifications

CAS Number

[119-61-9]

UNSPSC

12352005

Hazard Statement

H350, H373, H401, H412

Target

Endogenous Metabolite; Photosensitizer

Type

Natural Products

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/benzophenone.html

Concentration

10mM

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CC=C1)C2=CC=CC=C2

Molecular Formula

C13H10O

Molecular Weight

182.22

Precautions

H350, H373, H401, H412

References & Citations

[1]EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) ; Silano V, et al., Safety of benzophenone to be used as flavouring. EFSA J. 2017 Nov 14;15 (11) :e05013.|[2]Rhodes MC, et al., Carcinogenesis studies of benzophenone in rats and mice. Food Chem Toxicol. 2007 May;45 (5) :843-51.