Raptinal
Raptinal, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis. Raptinal is able to rapidly induce cancer cell death by directly activating the effector caspase-3, bypassing the activation of initiator caspase-8 and caspase-9[1][2].
Product Specifications
CAS Number
[1176-09-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Apoptosis; Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/raptinal.html
Purity
98.0
Solubility
DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=CC1(C2(C=O)C3=C(C4=C2C=CC=C4)C=CC=C3)C5=C(C6=C1C=CC=C6)C=CC=C5
Molecular Formula
C28H18O2
Molecular Weight
386.44
Precautions
H315, H319, H335
References & Citations
H. pyloriBIRC3
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 3
Available Sizes
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