JNJ0966
Product Specifications
UNSPSC Description
JNJ0966 is a highly selective MMP-9 zymogen inhibitor with an IC50 of 440 nM.
Target Antigen
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/JNJ0966.html
Purity
99.39
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=C(C2=CSC(NC3=C(OC)C=CC=C3)=N2)SC(NC(C)=O)=N1
Molecular Weight
360.45
References & Citations
[1]Scannevin RH, et al. Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) thatallosterically inhibits zymogen activation. J Biol Chem. 2017 Oct 27;292(43):17963-17974.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-103482/JNJ0966-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-103482/JNJ0966-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
315705-75-0
Available Sizes
Curated Selection
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