Iberverin

Iberverin (-Methylthiopropyl isothiocyanate) is a sulforaphane homolog. Iberverin has anticancer activity. Iberverin inhibits cell proliferation and migration. Iberverin induces mitochondrial-related apoptosis and intracellular reactive oxygen species[1].

Product Specifications

CAS Number

[505-79-3]

Product Name Alternative

3-Methylthiopropyl isothiocyanate

UNSPSC

12352211

Hazard Statement

H227, H301, H311, H315, H319, H331, H335, H400, H410

Target

Apoptosis; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/iberverin.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CSCCCN=C=S

Molecular Formula

C5H9NS2

Molecular Weight

147.26

Precautions

H227, H301, H311, H315, H319, H331, H335, H400, H410

References & Citations

[1]1. Zhang Y, et al. Iberverin exhibits antineoplastic activities against human hepatocellular carcinoma via DNA damage-mediated cell cycle arrest and mitochondrial-related apoptosis. Front Pharmacol. 2023 Dec 13;14:1326346.