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Serotonin-d4 (hydrochloride)

Serotonin-d4 (5-Hydroxytryptamine-d4) hydrochloride is the deuterium labeled Serotonin (hydrochloride) (HY-B1473) [1]. Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM[2].

Product Specifications

CAS Number

[2469263-61-2]

Product Name Alternative

5-Hydroxytryptamine-d4 (hydrochloride) ; 5-HT-d4 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302+H312+H332, H315, H319, H335

Target

5-HT Receptor; COMT; Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Field of Research

Others

Purity

99.22

Solubility

H2O : 200 mg/mL (ultrasonic)

Smiles

OC1=CC2=C(NC=C2C([2H])([2H])C([2H])([2H])N)C=C1.Cl

Molecular Formula

C10H9D4ClN2O

Molecular Weight

216.70

Precautions

H302+H312+H332, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Curated Selection

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