Rosmanol
Rosmanol could inhibit the oxidation of low density lipoprotein (LPL) and significantly inhibit lipopolysaccharide induced iNOS and COX-2 expression, with anti-inflammatory effect.
Product Specifications
CAS Number
[80225-53-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
COX
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Rosmanol.html
Purity
98.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1O[C@]2([H])[C@@H](O)C3=C(C(O)=C(O)C(C(C)C)=C3)[C@@]41CCCC(C)(C)[C@]24[H]
Molecular Formula
C20H26O5
Molecular Weight
346.42
Precautions
H302, H315, H319
References & Citations
[1]Cheng AC, et al. Rosmanol potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells. Food Chem Toxicol. 2011 Feb;49 (2) :485-93.|[2]Loussouarn M, et al. Carnosic Acid and Carnosol, Two Major Antioxidants of Rosemary, Act through Different Mechanisms. Plant Physiol. 2017 Nov;175 (3) :1381-1394.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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