Rosmanol

Rosmanol could inhibit the oxidation of low density lipoprotein (LPL) and significantly inhibit lipopolysaccharide induced iNOS and COX-2 expression, with anti-inflammatory effect.

Product Specifications

CAS Number

[80225-53-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

COX

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/Rosmanol.html

Purity

98.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1O[C@]2([H])[C@@H](O)C3=C(C(O)=C(O)C(C(C)C)=C3)[C@@]41CCCC(C)(C)[C@]24[H]

Molecular Formula

C20H26O5

Molecular Weight

346.42

Precautions

H302, H315, H319

References & Citations

[1]Cheng AC, et al. Rosmanol potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells. Food Chem Toxicol. 2011 Feb;49 (2) :485-93.|[2]Loussouarn M, et al. Carnosic Acid and Carnosol, Two Major Antioxidants of Rosemary, Act through Different Mechanisms. Plant Physiol. 2017 Nov;175 (3) :1381-1394.