LDV

LDV is a non-fluorescent analog of LDV-FITC. LDV is a α4β1 integrin (VLA-4) ligand, and binds α4β1 integrin in leukemia cells[1][2].

Product Specifications

CAS Number

[1155866-55-9]

UNSPSC

12352209

Target

Integrin

Type

Peptides

Related Pathways

Cytoskeleton

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ldv.html

Purity

99.27

Solubility

DMSO : ≥ 12.5 mg/mL

Smiles

NCCCC[C@@H](C(O)=O)NC([C@H](C)NC([C@H](C)NC([C@H]1N(C([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC(CC2=CC=C(NC(NC3=CC=CC=C3C)=O)C=C2)=O)=O)=O)=O)CCC1)=O)=O)=O

Molecular Formula

C48H70N10O12

Molecular Weight

979.13

References & Citations

[1]Ben H Njus, et al. Conformational mAb as a tool for integrin ligand discovery. Assay Drug Dev Technol. 2009 Oct;7 (5) :507-15.|[2]Estelle Gérard, et al. LDV peptidomimetics equipped with biotinylated spacer-arms: synthesis and biological evaluation on CCRF-CEM cell line. Bioorg Med Chem Lett. 2012 Jan 1;22 (1) :586-90.