11S(12R)-EET
Product Specifications
UNSPSC Description
11S(12R)-EET is a dominant enantiomer of epoxytrienoic acid (EET) that is metabolized at a higher rate in rat organs. It shows enantiomeric-dependent reaction selectivity in hydration, especially in the case of 11,12-EET, where water addition is non-regioselective, while in 8,9-EET, water addition occurs mainly at the C9 position. In addition, 11S(12R)-EET generates diol products with specific stereochemistry through enzymatic hydration reactions, which are affected by the selective recognition of epoxidases, reaction conversion rates, and substrate binding parameters[1].
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/11s-12r-eet.html
Smiles
OC(CCC/C=C\C/C=C\C[C@H]1[C@H](O1)C/C=C\CCCCC)=O
Molecular Weight
320.47
References & Citations
[1]Zeldin D C, et al. Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis[J]. Archives of biochemistry and biophysics, 1995, 316(1): 443-451.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N12962/11S-12R-EET-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N12962/
Clinical Information
No Development Reported
CAS Number
123931-40-8
Available Sizes
Curated Selection
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