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Anti-Crk2 monoclonal Antibody

Boster Bio Anti-Crk2 monoclonal Antibody catalog # M02533. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Adapter molecule crk; Proto-oncogene c-Crk; p38; CRK;

Gene Name

CRK

UniProt

P46108

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full length Human Crk2.

Clonality

Monoclonal

Applications

WB

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:1000

Form

Liquid

Function

Isoform Crk-II: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Molecular Weight

33831 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M02533

Product MSDS

https://www.bosterbio.com/msds?sku=M02533

Other Gene Names

Adapter molecule crk

Subcellular Location

Cytoplasm . Cell membrane . Translocated to the plasma membrane upon cell adhesion. .

Protein Name

Adapter molecule crk

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