Anti-TCEB2 ELOB Antibody
Boster Bio Anti-TCEB2 ELOB Antibody catalog # A31718. Tested in WB, IP applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Elongin-B; EloB; Elongin 18 kDa subunit; RNA polymerase II transcription factor SIII subunit B; SIII p18; Transcription elongation factor B polypeptide 2; ELOB
Gene Name
ELOB
UniProt
Q15370
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human TCEB2 (NP_009039.1) .
Clonality
Polyclonal
Applications
WB, IP
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (PubMed:7638163) . In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells (By similarity) .
Molecular Weight
13133 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A31718
Product MSDS
https://www.bosterbio.com/msds?sku=A31718
Other Gene Names
Elongin-B
Subcellular Location
Nucleus .
Protein Name
Elongin-B
Curated Selection
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