Anti-NTMT1 Antibody
Boster Bio Anti-NTMT1 Antibody catalog # A10023. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
N-terminal Xaa-Pro-Lys N-methyltransferase 1;2.1.1.244
Gene Name
NTMT1
UniProt
Q9BV86
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human NTMT1.
Clonality
Polyclonal
Applications
WB, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation (PubMed:24090352) . Catalyzes the trimethylation of the N-terminal Gly in CENPA (after removal of Met-1) . Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.
Molecular Weight
25387 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A10023
Product MSDS
https://www.bosterbio.com/msds?sku=A10023
Other Gene Names
N-terminal Xaa-Pro-Lys N-methyltransferase 1
Subcellular Location
Nucleus
Protein Name
N-terminal Xaa-Pro-Lys N-methyltransferase 1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1194493-01 0.02 mg (E-Coli)
Recombinant Candida albicans Guanine nucleotide-binding protein subunit beta-like protein (ASC1)
Ask
View Details