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Anti-Integrin alpha-8 ITGA8 Antibody

Boster Bio Anti-Integrin alpha-8 ITGA8 Antibody catalog # A06636. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Integrin alpha-8; Integrin alpha-8 heavy chain; Integrin alpha-8 light chain; ITGA8;

Gene Name

ITGA8

UniProt

P53708

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human ITGA8.

Clonality

Polyclonal

Tissue Specificity

Expressed in mesenchymal cells, including alveolar myofibroblasts, kidney mesangial cells and hepatic stellar cells and vascular and visceral smooth muscle (at protein level) .

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:1000

Form

Liquid

Function

Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.

Molecular Weight

117474 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06636

Product MSDS

https://www.bosterbio.com/msds?sku=A06636

Other Gene Names

Integrin alpha-8

Subcellular Location

Membrane

Protein Name

Integrin alpha-8

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