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Anti-CDK10 (E63) Antibody

Boster Bio Anti-CDK10 (E63) Antibody catalog # A06507. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Cyclin-dependent kinase 10;2.7.11.22; Cell division protein kinase 10; Serine/threonine-protein kinase PISSLRE; CDK10;

Gene Name

CDK10

UniProt

Q15131

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 30-84 of Human Cdk10.

Clonality

Polyclonal

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

IHC: 1:50-1:200

Form

Liquid

Function

Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) (PubMed:24218572) . Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling (PubMed:27104747) .

Molecular Weight

41038 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06507

Product MSDS

https://www.bosterbio.com/msds?sku=A06507

Other Gene Names

Cyclin-dependent kinase 10

Subcellular Location

Cytoplasm, cytoskeleton, cilium basal body

Protein Name

Cyclin-dependent kinase 10

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