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Anti-PACSIN2 Antibody

Boster Bio Anti-PACSIN2 Antibody catalog # A04211. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Protein kinase C and casein kinase substrate in neurons protein 2; Syndapin-2; Syndapin-II; PACSIN2;

Gene Name

PACSIN2

UniProt

Q9UNF0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human PACSIN2 (NP_009160.2) .

Clonality

Polyclonal

Tissue Specificity

Widely expressed.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.

Molecular Weight

55739 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04211

Product MSDS

https://www.bosterbio.com/msds?sku=A04211

Other Gene Names

Protein kinase C and casein kinase substrate in neurons protein 2

Subcellular Location

Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Recycling endosome membrane. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection . Membrane, caveola. Detected at the neck of flask-shaped caveolae. Localization to tubular recycling endosomes probably requires interaction with MICALL1 and EHD1.

Protein Name

Protein kinase C and casein kinase substrate in neurons protein 2

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