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Anti-GRB14 (D123) Antibody

Boster Bio Anti-GRB14 (D123) Antibody catalog # A04177. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Growth factor receptor-bound protein 14; GRB14 adapter protein; GRB14;

Gene Name

GRB14

UniProt

Q14449

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 90-102 of Human GRB14.

Clonality

Polyclonal

Tissue Specificity

Expressed at high levels in the liver, kidney, pancreas, testis, ovary, heart and skeletal muscle.

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

IHC: 1:50-1:200

Form

Liquid

Function

Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR) . Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

Molecular Weight

60988 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04177

Product MSDS

https://www.bosterbio.com/msds?sku=A04177

Other Gene Names

Growth factor receptor-bound protein 14

Subcellular Location

Cytoplasm

Protein Name

Growth factor receptor-bound protein 14

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