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Anti-Nuclear RNA export factor 1 NXF1 Antibody

Boster Bio Anti-Nuclear RNA export factor 1 NXF1 Antibody catalog # A02137. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Nuclear RNA export factor 1; Tip-associated protein; Tip-associating protein; mRNA export factor TAP; NXF1; TAP;

Gene Name

NXF1

UniProt

Q9UBU9

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide, corresponding to amino acids 1-45 of Human NXF1

Clonality

Polyclonal

Tissue Specificity

Expressed ubiquitously.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Dilution

WB: 1:500-1:1000

Form

Liquid

Function

Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway) (PubMed:10924507) . The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex (PubMed:18364396, PubMed:19165146, PubMed:9660949) . ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export (PubMed:18364396, PubMed:19165146, PubMed:9660949) . Also involved in nuclear export of m6A-containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export (PubMed:28984244) .

Molecular Weight

70182 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02137

Product MSDS

https://www.bosterbio.com/msds?sku=A02137

Other Gene Names

Nuclear RNA export factor 1

Subcellular Location

Nucleus

Protein Name

Nuclear RNA export factor 1

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