Anti-SREBF2 Antibody
Boster Bio Anti-SREBF2 Antibody catalog # A01678-1. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Sterol regulatory element-binding protein 2; SREBP-2; Class D basic helix-loop-helix protein 2; bHLHd2; Sterol regulatory element-binding transcription factor 2; Processed sterol regulatory element-binding protein 2; SREBF2; BHLHD2, SREBP2;
Gene Name
SREBF2
UniProt
Q12772
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human SREBF2
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed in adult and fetal tissues.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity) . Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes. .
Molecular Weight
123688 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A01678-1
Product MSDS
https://www.bosterbio.com/msds?sku=A01678-1
Other Gene Names
Sterol regulatory element-binding protein 2
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Moves from the endoplasmic reticulum to the Golgi in the absence of sterols.
Protein Name
Sterol regulatory element-binding protein 2
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