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Anti-HCLS1-associated protein X-1 HAX1 Antibody

Boster Bio Anti-HCLS1-associated protein X-1 HAX1 Antibody catalog # A01495-1. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

HCLS1-associated protein X-1; HS1-associating protein X-1; HAX-1; HS1-binding protein 1; HSP1BP-1; HAX1; HS1BP1;

Gene Name

HAX1

UniProt

O00165

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human HAX1 (NP_006109.2) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Up-regulated in oral cancers.

Applications

WB, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex (PubMed:26997484) . Slows down the rate of inactivation of KCNC3 channels (PubMed:26997484) . Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.

Molecular Weight

31621 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01495-1

Product MSDS

https://www.bosterbio.com/msds?sku=A01495-1

Other Gene Names

HCLS1-associated protein X-1

Subcellular Location

Mitochondrion

Protein Name

HCLS1-associated protein X-1

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