Anti-Fructose-1,6-bisphosphatase 1 FBP1 Antibody
Boster Bio Anti-Fructose-1,6-bisphosphatase 1 FBP1 Antibody catalog # A01377. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Fructose-1,6-bisphosphatase 1; FBPase 1;3.1.3.11
Gene Name
FBP1
UniProt
P09467
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human FBP1 (NP_000498.2) .
Clonality
Polyclonal
Tissue Specificity
Expressed in pancreatic islets.
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Molecular Weight
36842 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A01377
Product MSDS
https://www.bosterbio.com/msds?sku=A01377
Other Gene Names
Fructose-1,6-bisphosphatase 1
Protein Name
Fructose-1,6-bisphosphatase 1
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