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Anti-IL-4R Alpha (G493) Antibody

Boster Bio Anti-IL-4R Alpha (G493) Antibody catalog # A00807. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124; Soluble interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble IL-4R-alpha; sIL4Ralpha/prot; IL-4-binding protein; IL4-BP; IL4R; IL4RA;582J2.1;

Gene Name

IL4R

UniProt

P24394

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 460-510 of Human IL-4Rα.

Clonality

Polyclonal

Tissue Specificity

Isoform 1 and isoform 2 are highly expressed in activated T-cells.

Applications

WB, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

Molecular Weight

89658 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00807

Product MSDS

https://www.bosterbio.com/msds?sku=A00807

Other Gene Names

Interleukin-4 receptor subunit alpha

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Name

Interleukin-4 receptor subunit alpha

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