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Anti-Homeobox protein Nkx-2.5 NKX2-5 Antibody

Boster Bio Anti-Homeobox protein Nkx-2.5 NKX2-5 Antibody catalog # A00738. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Homeobox protein Nkx-2.5; Cardiac-specific homeobox; Homeobox protein CSX; Homeobox protein NK-2 homolog E; NKX2-5; CSX, NKX2.5, NKX2E;

Gene Name

NKX2-5

UniProt

P52952

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human NKX2-5 (NP_004378.1) .

Clonality

Polyclonal

Tissue Specificity

Expressed only in the heart.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity) . Binds to the core DNA motif of NPPA promoter (PubMed:22849347, PubMed:26926761) . It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity) . It is required for spleen development.

Molecular Weight

34918 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00738

Product MSDS

https://www.bosterbio.com/msds?sku=A00738

Other Gene Names

Homeobox protein Nkx-2.5

Subcellular Location

Nucleus .

Protein Name

Homeobox protein Nkx-2.5

Curated Selection

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