Anti-p73 (phospho-Y99) TP73 Antibody
Boster Bio Anti-p73 (phospho-Y99) TP73 Antibody catalog # A00688Y99. Tested in IHC applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Tumor protein p73; p53-like transcription factor; p53-related protein; TP73; P73;
Gene Name
TP73
UniProt
O15350
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic phosphopeptide derived from human p73 around the phosphorylation site of Tyrosine 99.
Clonality
Polyclonal
Tissue Specificity
Expressed in striatal neurons of patients with Huntington disease (at protein level) . Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue.
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
IHC: 1:50-1:200
Form
Liquid
Function
Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Molecular Weight
69623 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A00688Y99
Product MSDS
https://www.bosterbio.com/msds?sku=A00688Y99
Other Gene Names
Tumor protein p73
Subcellular Location
Nucleus
Protein Name
Tumor protein p73
Curated Selection
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