CTTHWGFTLC, CYCLIC (TFA)
Product Specifications
UNSPSC Description
CTTHWGFTLC, CYCLIC TFA is a cyclic peptide inhibitor for matrix metalloproteinases MMP-2 and MMP-9. The IC50 value for MMP-9 is ~8 μM[1].
Target Antigen
MMP
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ctthwgftlc-cyclic-tfa.html
Purity
98.91
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(N[C@H]1CC2=CNC3=CC=CC=C23)[C@H](CC4=CN=CN4)NC([C@]([H])([C@@H](C)O)NC([C@]([H])([C@@H](C)O)NC([C@@H](N)CSSC[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@]([H])([C@@H](C)O)NC([C@H](CC5=CC=CC=C5)NC(CNC1=O)=O)=O)=O)=O)=O)=O)=O.O=C(C(F)(F)F)O
Molecular Weight
1280.35
References & Citations
[1]Medina OP, et al. Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro. Cancer Res. 2001 May 15;61(10):3978-85.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1789A/CTTHWGFTLC-CYCLIC-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1789A/CTTHWGFTLC-CYCLIC-TFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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