Acitazanolast

Acitazanolast is an orally active antiallergic agent, can inhibit histamine release. Acitazanolast can be used in study of type I anaphylaxis (immediate) caused by IgE antibodies[1].

Product Specifications

CAS Number

[114607-46-4]

Product Name Alternative

WP-871

UNSPSC

12352005

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/acitazanolast.html

Purity

98.70

Solubility

DMSO : 35.71 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NC1=CC=CC(C2=NN=NN2)=C1)C(O)=O

Molecular Formula

C9H7N5O3

Molecular Weight

233.18

References & Citations

[1]Kamei C, et al. Effect of an active metabolite of the antiallergic agent tazanolast on histamine release from rat mast cells. Arzneimittelforschung. 1997 Apr;47 (4) :390-4. |[2]Kamei C, et al. Effect of an active metabolite of the antiallergic agent tazanolast on histamine release from rat mast cells. Arzneimittelforschung. 1997 Apr;47 (4) :390-4.