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Methoxsalen

Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.

Product Specifications

CAS Number

[298-81-7]

Product Name Alternative

8-Methoxypsoralen; Xanthotoxin; 8-MOP

UNSPSC

12352005

Hazard Statement

H302, H317, H341, H351

Target

Cytochrome P450

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/Methoxsalen.html

Concentration

10mM

Purity

99.98

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL

Smiles

O=C1OC(C(C=C1)=C2)=C(OC)C3=C2C=CO3

Molecular Formula

C12H8O4

Molecular Weight

216.19

Precautions

H302, H317, H341, H351

References & Citations

[1]Alsharari SD, et al. Pharmacokinetic and Pharmacodynamics Studies of Nicotine After Oral Administration in Mice: Effects of Methoxsalen, a CYP2A5/6 Inhibitor. Nicotine Tob Res. 2014 Jan;16 (1) :18-25.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

Launched

Available Sizes

Curated Selection

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