Cav2.2 rabbit pAb

Calcium voltage-gated channel subunit alpha1 B (CACNA1B) Homo sapiens The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],

Product Specifications

Background

UniProt

Q00975

Swiss Prot

Q00975

Reactivity

Human; Rat; Mouse

Immunogen

Synthetic Peptide of Cav2.2 AA range: 230-310

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF

Concentration

1 mg/ml

Dilution

IHC 1:50-100

Molecular Weight

263kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

263kD

Fragment

IgG

Subcellular Location

Membrane ; Multi-pass membrane protein .

Other Product Names

Voltage-dependent N-type calcium channel subunit alpha-1B (Brain calcium channel III; BIII; Calcium channel, L type, alpha-1 polypeptide isoform 5; Voltage-gated calcium channel subunit alpha Cav2.2)