N-Nitrosodibenzylamine-d4
Product Specifications
UNSPSC Description
N-Nitrosodibenzylamine-d4 is deuterium labeled N-Nitrosodibenzylamine. N-Nitrosodibenzylamine is a potent and orally activity DNA damage inducer. N-Nitrosodibenzylamine induces DNA single-strand breaks (SSBs)[1][2].
Target Antigen
DNA/RNA Synthesis; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage;Others
Field of Research
Others
Smiles
[2H]C(C1=CC=CC=C1)([2H])N(N=O)C([2H])([2H])C2=CC=CC=C2
Molecular Weight
230.30
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Appel KE, et al. DNA damage induced by N-nitrosodibenzylamine and N-nitroso-alpha-acetoxybenzyl-benzylamine in mammalian cell systems and in vivo. Toxicol Lett. 1990 Aug;52(3):269-77.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
20002-23-7
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