Tobevibart
Tobevibart (VIR-3434) is a human IgG1 lambda monoclonal antibody against hepatitis B virus (HBV) surface antigen (HBsAg) . Tobevibart shows potent neutralization against HBsAg from all HBV genotypes in vitro and inhibits viral entry of HBV and hepatitis delta virus (HDV) . Recommend Isotype Controls: Human IgG1 lambda2, Isotype Control (HY-P990096) [1].
Product Specifications
CAS Number
[2645440-65-7]
Product Name Alternative
VIR-3434
UNSPSC
12352203
Target
HBV
Type
Inhibitory Antibodies
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tobevibart.html
Purity
99.83
Solubility
H2O
Smiles
[Tobevibart]
Molecular Weight
(143.234 kDa)
References & Citations
[1]Jiayi Zhou, et al. Therapy with murinized tobevibart and elebsiran is efficacious in a liver-chimeric mouse model of HDV infection. JHEP Reports. 22 March 2025, 101400.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3
Available Sizes
Curated Selection
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