Hemin
Hemin is an iron-containing porphyrin. Hemin is an Heme oxygenase (HO) -1 inducer.
Product Specifications
CAS Number
[16009-13-5]
Product Name Alternative
Hemin chloride
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Autophagy; Ferroptosis; Mitophagy
Type
Natural Products
Related Pathways
Apoptosis; Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Hemin.html
Purity
99.59
Solubility
1M NaOH : 6.67 mg/mL (ultrasonic; adjust pH to 12 with NaOH) |H2O : < 0.1 mg/mL
Smiles
[Cl-][Fe+3]123[N-]4C5=C(CCC(O)=O)C(C)=C4C=C(C(C=C)=C6C)[N]1=C6C=C(C(C=C)=C7C)[N-]2C7=CC(C(C)=C8CCC(O)=O)=[N]3C8=C5
Molecular Formula
C34H32ClFeN4O4
Molecular Weight
651.94
Precautions
H315, H319, H335
References & Citations
[1]Vanova K, et al. Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells. BMC Cancer. 2016 May 12;16:309.|[2]Chen HH, et al. Heme oxygenase-1 ameliorates kidney ischemia-reperfusion injury in mice through extracellular signal-regulated kinase 1/2-enhanced tubular epithelium proliferation. Biochim Biophys Acta. 2015 Oct;1852 (10 Pt A) :2195-201.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Available Sizes
Curated Selection
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