Hispidol
Hispidol ((Z) -Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 μM.
Product Specifications
CAS Number
[5786-54-9]
Product Name Alternative
(Z) -Hispidol
UNSPSC
12352005
Hazard Statement
H315, H319
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Hispidol.html
Purity
98.30
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1C2=CC=C(O)C=C2O/C1=C\C3=CC=C(O)C=C3
Molecular Formula
C15H10O4
Molecular Weight
254.24
Precautions
H315, H319
References & Citations
[1]Kadayat TM, et al. Discovery and structure-activity relationship studies of 2-benzylidene-2,3-dihydro-1H-inden-1-one and benzofuran-3 (2H) -one derivatives as a novel class of potential therapeutics for inflammatory bowel disease. Eur J Med Chem. 2017 Sep 8;137:575-597.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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