Diacetolol

Diacetolol is an active metabolite of the beta-adrenoceptor blocking agent Acebutolol (HY-17497) [1].

Product Specifications

CAS Number

[22568-64-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/diacetolol.html

Purity

96.0

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC(NC1=CC=C(OCC(O)CNC(C)C)C(C(C)=O)=C1)=O

Molecular Formula

C16H24N2O4

Molecular Weight

308.38

Precautions

H302, H315, H319, H335

References & Citations

[1]B Basil, R Jordan, et al. Pharmacological properties of diacetolol (M & B 16,942), a major metabolite of acebutolol. Eur J Pharmacol. 1982 May 7;80 (1) :47-56.|[2]B Basil, R Jordan, et al. Pharmacological properties of diacetolol (M & B 16,942), a major metabolite of acebutolol. Eur J Pharmacol. 1982 May 7;80 (1) :47-56.