Thalidezine
Product Specifications
UNSPSC Description
Thalidezine is a novel activator of AMP-activated protein kinase (AMPK). Thalidezine can eliminate anti-apoptotic cancer cells through energy-mediated autophagy death. Thalidezine can be used to study apoptosis intervention [1].
Target Antigen
AMPK; Apoptosis
Type
Natural Products
Related Pathways
Apoptosis;Epigenetics;PI3K/Akt/mTOR
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thalidezine.html
Solubility
10 mM in DMSO
Smiles
COC1=C(O2)C3=C(CCN(C)[C@@]3([H])CC4=CC=C(OC)C(OC5=CC=C(C=C5)C[C@@]6([H])C7=C(CCN6C)C=C(OC)C2=C7)=C4)C(O)=C1OC
Molecular Weight
638.75
References & Citations
[1]Law BYK, et al. Thalidezine, a novel AMPK activator, eliminates apoptosis-resistant cancer cells through energy-mediated autophagic cell death. Oncotarget. 2017 May 2;8(18):30077-30091.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N6077/Thalidezine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N6077/
Clinical Information
No Development Reported
CAS Number
18251-36-0
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7151519 Inquire
Rabbit anti-Saccharomyces cerevisiae (strain 204508/S288c)(Baker's yeast) YML002W Polyclonal Antibody
Ask
View Details