Magnesium citrate

Magnesium citrate (Trimagnesium dicitrate) is an orally active magnesium-containing compound that can cross the blood-brain barrier (BBB) . Magnesium citrate can be used as an intestinal cleanser and is studied for its application in laxatives. Magnesium citrate can also increase the pain threshold and is studied for pain-relief purposes[1][2].

Product Specifications

CAS Number

[3344-18-1]

Product Name Alternative

Trimagnesium dicitrate

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/magnesium-citrate.html

Purity

98.0

Solubility

H2O : 4.72 mg/mL (ultrasonic; warming; adjust pH to 2 with HCl; heat to 60°C)

Smiles

C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[Mg+2].[Mg+2].[Mg+2]

Molecular Formula

C12H10Mg3O14

Molecular Weight

451.11

Precautions

H302, H315, H319, H335

References & Citations

[1]Koc B, et al. Magnesium Citrate Increases Pain Threshold and Reduces TLR4 Concentration in the Brain. Biol Trace Elem Res. 2021;199 (5) :1954-1966. |[2]Hoy SM, et al. Sodium picosulfate/magnesium citrate: a review of its use as a colorectal cleanser. Drugs. 2009;69 (1) :123-36.