APN-PEG5-VC-PAB-MMAE
Product Specifications
UNSPSC Description
APN-PEG5-VC-PAB-MMAE is a drug-linker conjugate part of INA03 (a transferrin-competitive antibody-drug conjugate against CD71)[1].
Target Antigen
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apn-peg5-vc-pab-mmae.html
Solubility
10 mM in DMSO
Smiles
N#CC#CC1=CC=C(N2N=NC(COCCOCCOCCOCCOCCC(N[C@H](C(N[C@H](C(NC3=CC=C(COC(N([C@@H](C(C)C)C(N[C@@H](C(C)C)N(C)[C@H]([C@H](OC)CC(N4CCC[C@]4([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C5=CC=CC=C5)=O)[H])=O)[C@@H](C)CC)=O)C)=O)C=C3)=O)CCCNC(N)=O)=O)C(C)C)=O)=C2)C=C1
Molecular Weight
1549.89
References & Citations
[1]Bratti M, et al. INA03, a potent transferrin-competitive antibody-drug conjugate against CD71, for a safer acute leukemia treatment. Mol Cancer Ther. 2024 Apr 20.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163549/APN-PEG5-VC-PAB-MMAE-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163549/
Clinical Information
No Development Reported
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