FG-3019

FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF) . FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF) [1][2].

Product Specifications

CAS Number

[946415-13-0]

Product Name Alternative

Pamrevlumab; Anti-Human CTGF Recombinant Antibody

UNSPSC

12352203

Target

Apoptosis

Type

Inhibitory Antibodies

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fg-3019.html

Purity

99.00

Solubility

H2O

Smiles

[FG-3019]

Molecular Weight

(144.86 kDa)

References & Citations

[1]Sgalla G, et, al. Pamrevlumab for the treatment of idiopathic pulmonary fibrosis. Expert Opin Investig Drugs. 2020 Aug;29 (8) :771-777.|[2]Neesse A, et, al. CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer. Proc Natl Acad Sci U S A. 2013 Jul 23;110 (30) :12325-30.