NR-V04
Product Specifications
UNSPSC Description
NR-V04 is a PROTAC based NR4A1 degrader (Red: NR4A1 inhibitor (HY-13067), black: linker, Blue: E3 ligase ligand)[1].
Target Antigen
Nuclear Hormone Receptor 4A/NR4A; PROTACs
Type
Reference compound
Related Pathways
PROTAC;Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nr-v04.html
Smiles
C[C@@]12[C@]([C@@]3([H])[C@@](CC1)(CC[C@](C)(C3)C(NCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@@H](C[C@H](C4)O)C(N[C@H](C5=CC=C(C6=C(N=CS6)C)C=C5)C)=O)=O)=O)=O)C)(CC[C@@]7(C2=CC=C8C7=CC(C(O)=C8C)=O)C)C
Molecular Weight
1110.45
References & Citations
[1]Weizhou ZHANG, et al. Modulators of nuclear receptor subfamily 4 group a member 1 (nr4a1) and uses thereof. US, WO2022072094. 2022-04-07.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159779/NR-V04-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159779/
Clinical Information
No Development Reported
CAS Number
2766608-52-8
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