Preclamol (hydrochloride)

Preclamol hydrochloride ((-) -3-PPP hydrochloride) is a selective dopamine autoreceptor agonist. Preclamol hydrochloride has the potential for the research of schizophrenia[1][2].

Product Specifications

CAS Number

[88768-67-6]

Product Name Alternative

(-) -3-PPP (hydrochloride)

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/preclamol-hydrochloride.html

Purity

98.0

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCCN1C[C@H](C2=CC(O)=CC=C2)CCC1.Cl

Molecular Formula

C14H22ClNO

Molecular Weight

255.78

References & Citations

[1]Seth-Olov Thorberg, et al. Large scale synthesis and absolute configuration of (-) -3-ppp, a selective dopamine autoreceptor agonist. Tetrahedron. 1985, 41 (1) : 129-139.|[2]Tamminga CA, et al. Pharmacologic properties of (-) -3PPP (preclamol) in man. J Neural Transm Gen Sect. 1992;88 (3) :165-75.