CDK9-IN-1
CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection, with an IC50 of 39 nM for CDK9/CycT1, extracted from reference, compound 87.
Product Specifications
CAS Number
[1415559-43-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CDK; HIV
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cdk9-in-1.html
Concentration
10mM
Purity
98.52
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=C(NS(C)(=O)=O)C=C(NC2=NC=NC(C3=CC=CC(N4C(C5=C(C=CC=C5)C4=O)=O)=C3)=C2)C=C1
Molecular Formula
C26H21N5O4S
Molecular Weight
499.54
Precautions
H302, H315, H319, H335
References & Citations
[1]Nemeth G, et al. Novel, selective CDK9 inhibitors for the treatment of HIV infection. Curr Med Chem. 2011;18 (3) :342-358.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK9; HIV-1
Available Sizes
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