ABMA

ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite. ABMA selectively acts at host cell late endosomes rather than targeting toxin or pathogen itself. ABMA has broad-spectrum anti-infection activity[1][2].

Product Specifications

CAS Number

[332108-65-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Bacterial; Dengue Virus; Flavivirus; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/abma.html

Purity

98.50

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

COC1=CC=C(Br)C=C1CNC2(C3)CC4CC3CC(C4)C2

Molecular Formula

C18H24BrNO

Molecular Weight

350.29

Precautions

H302, H315, H319

References & Citations

[1]Wu Y, et al. ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments.|[2]Wu Y, et al. DABMA: A Derivative of ABMA with Improved Broad-Spectrum Inhibitory Activity of Toxins and Viruses. ACS Med Chem Lett. 2019 Jul 2;10 (8) :1140-1147.