Maackiain

Maackiain (DL-Maackiain) is isolated from Maackia amurensis Rupr.et Maxim. Maackiain (DL-Maackiain) is a larvicidal agent against Aedes aegypti mosquito.xp Parasitol with a LD50 of 21.95 µg/mL[1]. Maackiain (DL-Maackiain) induces fragmentations of DNA to oligonucleosomal-sized fragments that like a characteristic of apoptosis in the HL-60 cells[2].

Product Specifications

CAS Number

[19908-48-6]

Product Name Alternative

DL-Maackiain

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Parasite

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/maackiain-1.html

Purity

99.83

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

OC1=CC=C2OC[C@]3([H])C4=CC5=C(OCO5)C=C4O[C@]3([H])C2=C1

Molecular Formula

C16H12O5

Molecular Weight

284.27

Precautions

H302, H315, H319, H335

References & Citations

[1]Bezerra-Silva PC, et al. Extract of Bowdichia virgilioides and maackiain as larvicidal agent against Aedes aegypti mosquito.xp Parasitol. 2015 Jun;153:160-4.|[2]Aratanechemuge Y, et al. Induction of apoptosis by maackiain and trifolirhizin (maackiain glycoside) isolated from sanzukon (Sophora Subprostrate Chen et T. Chen) in human promyelotic leukemia HL-60 cells.Oncol Rep. 2004 Dec;12 (6) :1183-8.